external-validation

AI-powered chest X-ray pneumonia detection with 86% accuracy and 96.4% sensitivity, validated on an independent (cross-operator) cohort of 485 pediatric samples. Built with TensorFlow & FastAPI.

预测模型自学教程：从数据清洗到模型外部验证（R 语言）

Developed ML algorisms on transcriptomics landscapes identi-fies SPON1 and ALDH1A2 as candidate prognostic biomarkers in TME and serous ovarian cancer progression

Reproducible regulatory transfer analysis for CRISPR interference in primary human CD4 T cells

Predictions-only calibration validation for binary clinical prediction models: cluster-aware, cross-fitted, report-emitting. Python.

Reproducible TCGA-LUAD survival pipeline on RNA-seq, clinical and mutation data. LASSO-Cox gene signature overfit (train C=0.722, test 0.538), reported as a negative finding; clinical Cox model (age, sex, grouped stage) validated on external cohort GSE31210 (C=0.708). Snakemake, Docker, FastAPI.

Interpretable TCGA-BRCA RNA-seq breast cancer subtype classification with ML, SHAP, pathway enrichment, and METABRIC external validation.

Physiology-informed ICU sepsis early-warning model (LightGBM) trained on one hospital system and externally validated on another, with calibration, subgroup analysis and SHAP interpretation.

Designed and validated a computational oncology pipeline for hepatocellular carcinoma using RNA expression data, integrating machine learning, survival analysis, SHAP explainability, tumor microenvironment deconvolution, and multi-cohort external validation for precision medicine applications.

Reproducible analysis notebooks for self-report–wearable measurement discrepancies, perceived stress, and external validation using Samsung Health and Fitbit datasets.

Independent, reproducible evaluation of diagnostic and predictive-ML classifiers from model outputs and labels only. Standard-library Python. Implements the published METH-0.2 method.

Reproducible pipeline for development and external validation of an early distant recurrence model in stage III colon cancer.

Heart disease prediction tested at a hospital the model never saw: leave-one-site-out AUROC, calibration, and conformal prediction sets on the 4-site UCI data

Reproducibility code, processed data, out-of-fold predictions, and machine-readable results for leakage-aware e-commerce product classification using Mercadona and Amazon Reviews 2023.

Independent external validation, recalibration & fairness audit of EchoNext-Mini (AI-ECG for structural heart disease) in MIMIC-IV

An evidence-driven weekly planning Skill that limits preparation and prompts early external validation.

Benchmark honesto de descriptores de imagen para clasificar lesiones cutaneas dermatoscopicas (ISIC): 390 combinaciones descriptor x algoritmo, control del efecto de lote y validacion externa entre instituciones. AUC 0.741 fuera del archivo de entrenamiento.

Analysis code and de-identified local validation cohort for a GCS-free long-term mortality model in critically ill patients with acute brain injury

Sports activity classification using wearable-device features, XGBoost, and external validation on unseen data.

Reproducibility package for auditing outcome-ascertainment drift in external clinical prediction-model validation.