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PuliJagadeesh/README.md

Jagadeesh Puli

Quantum Computing & AI Researcher

Quantum Error Correction · Autonomous AI Agents · Machine Learning from First Principles

Semantic Scholar LinkedIn GitHub


About

I am a researcher and MS student working at the intersection of quantum computing, autonomous AI systems, and mathematical machine learning. My work focuses on building fault-tolerant quantum algorithms, designing autonomous multi-agent pipelines for scientific discovery, and implementing ML optimization algorithms from first-principles mathematics.

I have published in IEEE and international conferences, with research cited across the machine learning and healthcare informatics communities.


Publications

Year Title Venue Citations
2023 High Performance Cervical Cancer Detection Using Gradient Boosting Algorithm and Bayesian Optimization IEEE ITT Citations
2023 Crop Doctor: A Comprehensive Crop Management System for Precision Agriculture River Publishers Citations

h-index: 1 · Total Citations: 11 · Source: Semantic Scholar


Research Areas

Quantum Error Correction & Variational Algorithms

Designing stabilizer circuits and fault-tolerant noise models for surface codes. Building high-speed minimum-weight perfect matching (MWPM) graph decoders using Stim, PyMatching, and Qiskit. Exploring variational quantum eigensolver (VQE) pipelines for near-term quantum hardware.

Autonomous AI Agents for Scientific Discovery

Building multi-agent AI frameworks for computational drug discovery — including molecular property prediction, target binding analysis, and autonomous pipeline orchestration using agentic architectures.

Machine Learning from First Principles

Implementing mathematical optimization algorithms from ground-truth derivations: gradient boosting with deviance loss functions, LASSO via homotopy path optimization, and sparse recovery methods — all built without high-level ML library abstractions.


Featured Projects

Autonomous QEC syndrome decoder implementing surface code circuits with Stim noise simulation, PyMatching MWPM decoding, and Qiskit integration. Includes threshold analysis across physical error rates and interactive Streamlit visualization.

Python Qiskit Stim PyMatching Streamlit

Applied variational quantum eigensolver implementations and syndrome decoding pipelines for quantum error correction research.

Python Qiskit Quantum Computing

Autonomous AI agent suite for hybrid drug discovery workflows — molecular property prediction, target binding analysis, and multi-agent orchestration for computational chemistry pipelines.

Python Agentic AI Cheminformatics Drug Discovery

Complete derivation and implementation of gradient boosting machines with deviance loss optimization, built entirely from mathematical first principles without scikit-learn.

Python Jupyter Optimization Machine Learning

LASSO regularization via the homotopy continuation path algorithm — implementing the full regularization path from the KKT conditions upward.

Python Optimization Sparse Recovery

High-performance web crawler with document indexing and search ranking engine. Implements crawling, parsing, inverted index construction, and TF-IDF based retrieval.

Python Information Retrieval Search Systems


Technical Stack

Quantum ComputingQiskit Stim PyMatching

Machine Learning & Data SciencePython NumPy Pandas scikit-learn Matplotlib Jupyter

AI & AgentsLangChain Streamlit

Tools & InfrastructureGit Linux VS Code


GitHub Stats

Open to research collaborations in quantum computing, quantum machine learning, and AI for science.

Pinned Loading

  1. Hybrid_Drug_Discovery_Agent Hybrid_Drug_Discovery_Agent Public

    Autonomous AI Agent suite for hybrid drug discovery, molecular property prediction & target binding

    Python

  2. Quantum-Error-Correction Quantum-Error-Correction Public

    Autonomous Quantum Error Correction (QEC) Syndrome Decoder using Stim, PyMatching MWPM, Qiskit & Streamlit

    Python

  3. Applied-VQE-and-Syndrome-Decoding-Pipelines Applied-VQE-and-Syndrome-Decoding-Pipelines Public

    Applied Variational Quantum Eigensolver (VQE) implementations and syndrome decoding pipelines for quantum error correction research

    Python

  4. gradient-boosting-deviance-boosting-from-first-principles gradient-boosting-deviance-boosting-from-first-principles Public

    Forked from Spring2025CS584/Project2

    Gradient Boosting & Deviance Loss Optimization implemented from first principles

    Jupyter Notebook

  5. lasso-homotopy-from-scratch lasso-homotopy-from-scratch Public

    Forked from Spring2025CS584/Project1

    LASSO Homotopy path optimization algorithm implemented from scratch

    Python

  6. web-crawler-search-engine web-crawler-search-engine Public

    High-performance web crawler, document indexer, and search ranking engine

    HTML