TIS Models Name M+/M- M++ Exv. #sep-P #sep-S #sep-B RNA DT13 DH N/A WCA 3 3 2 RNA DT15 Coulomb Coulomb mWCA 3 3 2 RNA DHT18 N/A RNA NHT19 DH PMF mWCA 4 4 2 DNA CHT18 DH N/A WCA 3 3 2 DNA TBA DH PMF Molecular topology Linear S: linear nucleic acid whose 5'-end starts from sugar Linear P: linear nucleic acid whose 5'-end starts from phosphate Circular: circular nucleic acid Number of particles Linear S Linear P Circular (always P) nucleotides N N N P N-1 N N S N N N B N N N nmp 3N-1 3N 3N Number of bonds Linear S Linear P Circular (always P) PS N-1 N N SB N N N SP N-1 N-1 N Total 3N-2 3N-1 3N Number of angles Linear S Linear P Circular (always P) PSB N-1 N N PSP N-2 N-1 N BSP N-1 N-1 N SPS N-1 N-1 N Total 4N-5 4N-3 4N Tertiary stacks tst-dist share with secondary stack (exclusive = False) exclusively tertiary stack alone (exclusive = True)